CCRN Practice Tests & Quizzes

The single most-tested body system on the CCRN exam. 17% of the CCRN.

• Hemodynamic monitoring (PA catheter, SVR, PAOP)
• ACS & STEMI — door-to-balloon 90 min
• Cardiogenic shock + vasoactive drugs

High-yield respiratory content covering ventilation/oxygenation, ABG interpretation, ARDS, COPD, PE, and mechanical ventilation. 15% of the CCRN.

• ABG interpretation step-by-step
• ARDS: Berlin criteria, prone, LTVV
• Mechanical ventilation modes & weaning

Sepsis & septic shock, MODS, MDROs/HAIs, toxic ingestions, and influenza. 14% of the CCRN.

• Sepsis Hour-1 Bundle + septic shock
• MODS: organ-by-organ failure
• Toxidromes & overdose antidotes

Stroke (ischemic vs hemorrhagic), increased ICP, status epilepticus, TBI, and brain death assessment. 12% of the CCRN.

• Stroke: ischemic vs hemorrhagic, tPA
• ICP management + Cushing’s triad
• Status epilepticus + brain death

DKA vs HHS, adrenal crisis, thyroid storm, myxedema coma, and SIADH vs DI. 5% of the CCRN.

• DKA vs HHS comparison
• Thyroid storm + myxedema coma
• SIADH vs DI (urine osm, sodium)

Acute pancreatitis, GI hemorrhage, hepatic failure, abdominal compartment syndrome, mesenteric ischemia, bowel obstruction/perforation, and drug-induced liver injury. 6% of the CCRN.

• Acute pancreatitis + Grey Turner / Cullen
• Hepatic failure + HE ladder
• Abdominal compartment syndrome

AKI with KDIGO staging, CKD, dialysis (HD/CRRT/PD), and electrolyte imbalances. 6% of the CCRN.

• AKI — KDIGO staging & pre/intra/post-renal
• CRRT vs iHD indications (AEIOU)
• Electrolyte imbalances + ECG

DIC, HIT, HELLP, transfusion reactions (TRALI/TACO), hemorrhagic shock classification, neutropenic precautions, and oncologic emergencies (TLS, leukostasis). 2% of the CCRN.

• DIC — consumption coagulopathy
• HIT: 4T score + argatroban
• TRALI vs TACO + transfusion reactions